LiNTf 2 - i Pr 2 NEt: A Catalytic System for the Acylation of Phenols and Primary Alcohols with Carboxylic Anhydrides | Synapse
February 28, 2026
LiNTf 2 - i Pr 2 NEt: A Catalytic System for the Acylation of Phenols and Primary Alcohols with Carboxylic Anhydrides
Puntos clave
The research aims to develop a method for acylating phenols and primary alcohols using a specific catalytic system.
Utilized a binary catalytic system of LiNTf2 and iPr2NEt
Performed acylation reactions with carboxylic anhydrides
Assessed the system's steric inertness
Successfully catalyzed the acylation reaction of phenols
Demonstrated efficient acylation of primary alcohols
Showed good selectivity without significant steric hindrance
Resumen
A method for the acylation of phenols and primary alcohols with carboxylic anhydrides in the presence of LiNTf2 and iPr2NEt is described. The binary catalytic system is inert towards sterically...