PulseExploreJournal ClubDebatesTrendingResearchersJournals
Instagram
HomeExploreJournal ClubTrending
Synapse
⌘+K
Synapse
February 28, 2026Diabetes Care2 citations

Relationships Between Regional and Ectopic Adiposity and Insulin Sensitivity in Early and Late Pregnancy

View Full Paper
JPJonathan Q. PurnellNMNicole E. MarshallMFMelanie Francisco

Key Points

  • This research investigates how regional and ectopic adiposity affect insulin sensitivity in early versus late pregnancy.
  • Analyzed insulin resistance and adiposity in different pregnancy stages.
  • Categorized participants based on prepregnancy weight.
  • Assessed glucose metabolism related to fat distribution.
  • Insulin resistance in early pregnancy correlates strongly with adiposity levels.
  • In late pregnancy, other factors overshadow the influence of adiposity on insulin sensitivity.
  • Prepregnancy weight categories impact weight gain and metabolic responses.

Abstract

Insulin resistance in early pregnancy is strongly associated with total, regional, and ectopic adiposity. However, in late pregnancy, factors other than regional and ectopic adiposity predominately influence insulin sensitivity. Prepregnancy weight categories proportionately alter gestational weight gain, adiposity distribution, and glucometabolic responses.

Ask AI
Helpful
Bookmark
Share
View Full Paper

Cite This Study

Purnell et al. (2026) studied this question.

synapsesocial.com/papers/69a286850a974eb0d3c01879https://doi.org/10.2337/dc25-2081
Ask AI
Helpful
Bookmark
Share
View Full Paper