Multisite collaboration shows cold water immersion improves outcomes in heat stroke patients, suggesting operational feasibility.
A prehospital CWI protocol is feasible in a large urban EMS system and provides rapid temperature reduction and improved neurologic status in patients with heat stroke. The findings suggest a meaningful clinical benefit and broad operational feasibility. Further prospective, multicenter studies are needed to define the resulting impact, optimize workflows, and guide wider adoption of prehospital immersion cooling.
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Comp et al. (2026) studied this question.
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