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February 28, 2026BMC Anesthesiology0 citationsOpen Access

Respiratory effects of rectus sheath block in patients undergoing major upper abdominal surgery: a randomized controlled trial

NENoha Yahia Mohammd El-hagagyBGBeshoy Baligh Bolis GayeedMAMohamed Mohamed Abdel-Latif

Key Points

  • Evaluate the analgesic efficacy and respiratory effects of ultrasound-guided rectus sheath block (RSB) in patients undergoing upper abdominal surgery.
  • Conducted a randomized controlled trial with 60 patients aged 18–62 years.
  • Patients were divided into RSB group receiving ultrasound-guided RSB and control group without it.
  • Analgesic outcomes were measured using pain scores, opioid consumption, and pulmonary function tests post-surgery.
  • RSB group experienced significantly lower pain scores and reduced opioid consumption.
  • Diaphragmatic inspiratory amplitude decreased postoperatively in both groups but without significant intergroup differences.
  • Both groups showed comparable declines in pulmonary function measures like FVC and FEV1, indicating that RSB did not impair respiratory function.

Abstract

Postoperative pulmonary complications remain a major concern after upper abdominal surgery and are often exacerbated by either inadequate pain control or opioid-based analgesia. We evaluated the analgesic efficacy and respiratory effects of ultrasound-guided RSB in patients undergoing upper abdominal surgery. In this prospective, randomized, controlled trial, 60 patients aged 18–62 years, with ASA I or II status, who underwent upper abdominal surgery under general anesthesia, were enrolled and divided into two groups (30 patients each). RSB Group received ultrasound-guided rectus sheath block after induction of general anesthesia with 40 ml volume of 0.25% bupivacaine and 8 mg dexamethasone (half the volume on each side). The control group received standard anesthesia care without RSB. Pain scores, opioid consumption, diaphragmatic inspiratory amplitude (DIA), and pulmonary function tests were assessed in the immediate postoperative period. Diaphragmatic inspiratory amplitude decreased significantly from baseline at 6, 12, and 24 h postoperatively in both groups (P value < 0.001) with no significant intergroup differences. Forced vital capacity (FVC), forced expiratory volume in first second (FEV1) and Peak expiratory flow rate (PEFR) declined postoperatively in both groups but remained comparable between groups. The RSB group demonstrated significantly lower early postoperative pain scores (P = 0.007), delayed time to first rescue analgesia, reduced total opioid consumption (P < 0.001), and higher patient satisfaction (P = 0.041) with reduced incidence of side effects compared with controls. RSB provided effective opioid-sparing analgesia without impairing pulmonary function. Its simplicity, safety, and compatibility with enhanced recovery after surgery (ERAS) protocols highlight its role as a valuable adjunct to multimodal analgesia in upper abdominal surgery.

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Cite This Study

El-hagagy et al. (2026) studied this question.

synapsesocial.com/papers/69a287350a974eb0d3c02c2fhttps://doi.org/10.1186/s12871-026-03666-6
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