Synthesis Evaluation of Antibacterial Activity of New Derivatives of 1,3-Diaza-2-phenylamino-, 7-Amino-1,3,5-triaza-, 7-Carbamoylphenylamino-1,3,5-triazadamantanes

A number of new derivatives of diaza- and triazadamantanes were synthesized and their antibacterial activity was studied by the interaction of 2-(4-aminophenyl)-5,7-disubstituted-1,3-diazadamantanes, 1,3,5-triazadamantan-7-amine and 1,3,5-triazadamantan-7-yl-(aminophenyl)methanones with anhydrides of substituted succinic and glutaric acids. Among the synthesized compounds, some possess moderate activity, suppressing the growth of gram-positive and gram-negative microorganisms in a zone with a diameter of d = 14–16 mm.