Key result
The protocol defines sign-flip under respiration phase with pass criteria as R_inphase > 0 and R_antiphase < 0 and requires >50% dyads passing with p<0.025 for group-level success, with minimum 28 valid dyads for 80% power.
Effect estimate: Exact binomial test p-value threshold 0.025 for pass condition with minimum 28 dyads
This is a pre-registered experimental protocol for testing respiration phase synchrony, presenting no clinical claims or results.
Provides no current clinical guidance; extends research via pre-registered, powered criteria for respiration phase synchrony.
QCRM-Audit v1.0 is a pre-registered, audit-first experimental protocol designed to test a single primary endpoint (sign-flip) under a strictly frozen specification. This record contains three artefacts: MAIN: the full protocol (PASS/FAIL/INCOMPLETE gates, NO OVERCLAIM, and frozen parameters) SI: supplementary operational definitions and audit templates RUN_SHEET: the fixed run sheet for reproducible execution (constants and procedures fully specified) Scope and non-claims: This is a protocol specification, not a completed measurement study. No clinical or medical claims are made. No performance claims are made. This work is intended for peaceful, non-coercive, dignity-first research. Primary endpoint (v1.0): sign-flip: R > 0 at Δθ ≈ 0 and R < 0 at Δθ ≈ π Operational definition: Δθ := respiratory phase difference PLR threshold and audit gates are frozen in the files. Related work: This protocol is intended to be read alongside the foundational QCRM theory record:https://zenodo.org/records/17816492 Files: QCRM_Audit_v1.0_MAIN.txt / .pdf QCRM_Audit_v1.0_SI.txt / .pdf RUN_SHEET_QCRM_Audit_v1.0.txt / .pdf How to use: Read MAIN first. Use RUN_SHEET for execution without post-hoc adjustments. Use SI for definitions, audit templates, and reporting discipline.
No takes yet. Share an insight, caveat, or question.
Hisashi Suga (2026) studied Dyads of two participants measured simultaneously with respiration phase monitoring. Respiration phase synchrony manipulation at target phase differences (in-phase at Δθ=0 vs anti-phase at Δθ=π) vs. Comparison between in-phase and anti-phase respiration phase windows within dyads was evaluated on Sign-flip defined as R_inphase > 0 and R_antiphase < 0 tested at group level by exact binomial test with one-sided α=0.025 (Exact binomial test p-value threshold 0.025 for pass condition with minimum 28 dyads). The protocol defines sign-flip under respiration phase with pass criteria as R_inphase > 0 and R_antiphase < 0 and requires >50% dyads passing with p<0.025 for group-level success, with minimum 28 valid dyads for 80% power.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: