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February 28, 2026Biomaterials Science0 citations

MOF-reinforced NIR-responsive composite hydrogel with photothermal antibacterial and antioxidant activities for diabetic wound healing

ZZZ.J. ZhangYWYuxin WangBSBingjie Sun

Key Points

  • To develop a composite hydrogel with antibacterial and antioxidant properties for treating diabetic wounds.
  • Synthesis of a dual-cross-linked composite hydrogel incorporating metal-organic frameworks (MOFs).
  • Evaluation of the hydrogel's responsiveness to near-infrared (NIR) light.
  • Investigation of antibacterial effects and antioxidant activity against reactive oxygen species (ROS).
  • The composite hydrogel effectively reduced bacterial growth in laboratory tests.
  • Significant reduction in oxidative stress markers was observed.
  • Enhanced healing rates in diabetic wound models were reported.

Abstract

Chronic diabetic wounds are marked by recurrent infection, persistent ROS and prolonged inflammation. Herein, we report a MOF-reinforced NIR-responsive composite hydrogel (CEPN) that features a dual-cross-linked network assembled from carboxymethyl...

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Cite This Study

Zhang et al. (2026) studied this question.

synapsesocial.com/papers/69a287f20a974eb0d3c03de1https://doi.org/10.1039/d6bm00157b
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