Findings reveal EGFRvIII presence associated with signet-ring cell subtype in gastric adenocarcinoma, highlighting implications for treatment.
Our findings showed detection of EGFRvIII in 9.5% of gastric adenocarcinoma cases. Although the sample size presents a limitation, the increase in expression of this variant appears to be independent of the patients' gender and age. Notably, the association of this variant with the signet-ring cell adenocarcinoma subtype is a significant finding that warrants further investigation.
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Zare‐Mirzaie et al. (2026) studied this question.
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