Experiments show rapamycin improves behavior and reduces amyloid plaques in mice, suggesting potential for Alzheimer's treatment.
Our findings suggest that rapamycin reduces amyloid pathology and associated behavioral deficits in AD mice, an effect associated with enhanced microglial lysosomal activity and Aβ clearance, highlighting its therapeutic potential in AD treatment.
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Guo et al. (2026) studied this question.
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