Experimental investigation reveals antioxidant properties and weak COX-1 inhibition of Mentha pulegium, suggesting potential medicinal use.
People have used medicinal and aromatic plants and spices for centuries in order to treat diseases. Mentha pulegium is utilized as food in the world and in Turkiye and also a medicinal plant in traditional treatments. In this context, this study was carried out to examine the antioxidant and antimicrobial properties of the Mentha pulegium plant and its effects on cyclooxygenase-1 enzyme. While antioxidant properties were investigated spectrophotometrically by using 2,2-diphenyl-1-picrylhydrazyl, free radical test and Cupric Reducing Antioxidant Capacity assay methods, antibiotic effect was determined by using disc diffusion method. The effects on cyclooxygenase-1 enzyme were determined colorimetrically using commercial kits. The results showed that Mentha pulegium plant had a significant antioxidant effect, but it did not have any antibiotic effect on Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli and Candida albicans strains. On the other hand, it exhibited a very weak inhibitory effect on the cyclooxygenase-1 enzyme. Consequently, the Mentha pulegium plant has an important antioxidant property and showed a very weak inhibitory effect on the cyclooxygenase-1 enzyme.
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KOÇYİĞİT et al. (2023) studied this question.
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