Quantifying uncertainty in calibration and clinical application of EBT-4 Gafchromic film dosimetry.

We identified an optimal calibration function that incorporates a linear term and a 2.5th-order component to accurately model the relationship between radiation dose and the netODc in the red channel. The significant variability in performance among calibration functions underscores the critical need for independent verification and transparent dosimetry tools. To address this, our study makes the full analysis code and data publicly available, facilitating independent validation and enhancing the accuracy, consistency, and reproducibility of film dosimetry in clinical practice.