Longitudinal urinary LAM measurements in pulmonary tuberculosis patients: preliminary observations

Key Points

• This research aims to evaluate the potential of urinary LAM as a non-invasive method for monitoring pulmonary tuberculosis.
• Longitudinal measurements of urinary LAM levels were conducted in patients with pulmonary tuberculosis.
• Sputum samples were analyzed concurrently to compare results with urinary LAM levels.
• Caution was advised in interpreting low-baseline urinary LAM results.
• Urinary LAM kinetics closely align with sputum-derived patterns in tuberculosis patients.
• Findings indicate the possibility of using urine as a reliable non-invasive specimen for TB monitoring.
• The need for larger cohort studies to validate these preliminary observations was emphasized.