Triangulating Associations Between Fruit Intake and Lung Cancer Risk: Evidence from GBD Estimates, Mendelian Randomization, and Real-World Validation.

Mengqing Liu; Qilin Hu; Xi Zhang; Zhaoqi Wu; Shiwei Wang; Yile Hu; Shun Xu; Zhe Xu; Ji Luo; Li Sun

doi:10.1093/oncolo/oyag069

February 27, 2026

Triangulating Associations Between Fruit Intake and Lung Cancer Risk: Evidence from GBD Estimates, Mendelian Randomization, and Real-World Validation.

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Key Points

This study aims to explore the relationship between fruit intake and lung cancer risk using multiple approaches.
Analyzed population-level data from Global Burden of Disease estimates
Utilized mendelian randomization to assess genetic associations
Conducted clinical validations of findings
Insufficient fruit intake is consistently linked to increased lung cancer risk
Findings are supported across different data sources
Strength of association indicates a potential modifiable risk factor

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Implication

Multi-method analysis shows insufficient fruit intake increases lung cancer risk, indicating a health concern.

Abstract

This multi-method study strengthens evidence that insufficient fruit intake may increase lung cancer risk, with consistent findings across population-level, genetic, and clinical data.

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Cite This Study

Liu et al. (2026) studied this question.

synapsesocial.com/papers/69a52de5f1e85e5c73bf11f9 https://doi.org/10.1093/oncolo/oyag069

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Triangulating Associations Between Fruit Intake and Lung Cancer Risk: Evidence from GBD Estimates, Mendelian Randomization, and Real-World Validation.

Key Points

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Implication

Abstract

Discussion

Cite This Study

Triangulating Associations Between Fruit Intake and Lung Cancer Risk: Evidence from GBD Estimates, Mendelian Randomization, and Real-World Validation.

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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