Effectiveness and Safety of Enteroscopy-Assisted ERP-Guided Versus EUS-Guided Pancreatic Duct Drainage for Pancreaticojejunostomy Strictures: A Multicenter Observational Study.

Shogo Ota; Hideyuki Shiomi; Yuki Fujii; Kazuyuki Matsumoto; Masataka Kano; Masaaki Shimatani; Naoki Fujita; Hideki Kamada; Saori Ueno; Takeshi Ogura; Mamoru Takenaka; Kae Nagao; Arata Sakai; Shuhei Shintani; Osamu Inatomi; Koh Kitagawa; Ryota Nakano; Mitsuhito Koizumi; Yoshiki Imamura; Akihisa Ohno; Nao Fujimori; Takaaki Tamura; Tsukasa Miyagahara; Mikio Nakajima; Masayuki Kitano

doi:10.1111/den.70128

Key Points

The study aims to compare the effectiveness and safety of enteroscopy-assisted ERP-guided pancreatic duct drainage versus EUS-guided drainage for pancreaticojejunostomy strictures.
Multicenter observational study design
Comparison of technical and clinical success rates
Assessment of safety measures after adjustments
Analysis of MPD diameter correlation with treatment outcomes
Development of treatment algorithm based on MPD size
EUS-PDD showed higher technical and clinical success than eERP-PDD
Safety profiles were comparable between both techniques
An MPD diameter of ≥ 5 mm linked to eERP-PDD failure
Proposed treatment algorithm for MPD size optimization
Requires prospective validation of findings

Implication

Observational study finds EUS-PDD shows higher success for pancreaticojejunostomy strictures, indicating future protocols.

Abstract

EUS-PDD demonstrated higher technical and clinical success than eERP-PDD for PJS, with comparable safety after adjustment. An MPD diameter ≥ 5 mm was associated with eERP-PDD failure. An MPD-based algorithm is proposed: eERP-PDD for MPD < 5 mm with EUS-PDD as salvage, and EUS-PDD for MPD ≥ 5 mm. This algorithm is hypothesis-generating and requires prospective validation.

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Cite This Study

Ota et al. (2026) studied this question.

synapsesocial.com/papers/69a52e34f1e85e5c73bf1ad7 https://doi.org/10.1111/den.70128

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Effectiveness and Safety of Enteroscopy-Assisted ERP-Guided Versus EUS-Guided Pancreatic Duct Drainage for Pancreaticojejunostomy Strictures: A Multicenter Observational Study.

Key Points

Implication

Abstract

Discussion

Cite This Study

Effectiveness and Safety of Enteroscopy-Assisted ERP-Guided Versus EUS-Guided Pancreatic Duct Drainage for Pancreaticojejunostomy Strictures: A Multicenter Observational Study.

Key Points

Implication

Abstract

Discussion

Cite This Study

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