What question did this study set out to answer?

The aim is to create and test a hydrogel with lotus leaf extract for its antibacterial effects against periodontal pathogens.

Development and characterization of a hydrogel containing active principles of lotus leaves (Nelumbo nucifera): An in vitro study

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This in vitro study evaluates an antibacterial hydrogel in periodontal disease, suggesting potential as a local treatment.

The aim is to create and test a hydrogel with lotus leaf extract for its antibacterial effects against periodontal pathogens.
Extracted lotus leaves using a hydroalcoholic Soxhlet method.
Incorporated the extract into a hydrogel formulation.
Assessed antibacterial activity against Fusobacterium nucleatum in vitro.
Determined minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC).
Evaluated physical characteristics including pH and consistency.
Lotus leaf extract showed significant antibacterial activity with an MIC and MBC of 600 μg/mL against F. nucleatum.
The hydrogel was green, clear, semisolid, and had a pH of 7.0, indicating suitability for periodontal use.
The hydrogel exhibited a uniform texture, demonstrating favorable physical characteristics for application.

Raj et al. (2025) studied this question.

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