Why the study?
Does Electrophysiology Study (EPS) with isoproterenol accurately assess the risk of high-risk accessory pathways compared to Exercise Stress Test in patients with pre-excitation?
Does Electrophysiology Study (EPS) with isoproterenol accurately assess the risk of high-risk accessory pathways compared to Exercise Stress Test in patients with pre-excitation?
Sudden loss of pre-excitation during exercise stress testing is insufficient to rule out high-risk accessory pathways, supporting the use of EPS with isoproterenol for accurate risk assessment.
Sudden loss of pre-excitation during EST has a low NPV in excluding high-risk APs. The EPS with the use of isoproterenol should be considered to accurately assess the risk of patients with pre-excitation regardless of symptoms (ClinicalTrials.gov Identifier: NCT03301935).
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Jemtrén et al. (2024) studied this question.
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