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April 17, 2007Gut106 citationsOpen Access

Risks and benefits of biologic therapy for inflammatory bowel diseases

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Geert D’Haens
Geert D’HaensUniversité Paris-Sud

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Abstract

Methods of infant pulmonary function testing (IPFT) represent an important diagnostic tool for an assessment of chronic lung disease in infancy (CLDI). We assessed lung function in a cohort of children with a perinatal burden. We tested 74 infants and toddlers (birth weight 1.47±1.11kg mean±SD; body length at birth 30.8±16.3cm with CLDI. Age at testing was 1.38±0.69 (median 1.35) yrs; body weight 9.0±2.2kg, body length 76.0±9.7cm. The whole-body plethysmography (to measure FRCp and sReff), tidal breathing analysis (tPTEF%tE), baby resistance/compliance (specific Crs) and rapid thoraco-abdominal compression method (VmaxFRC) were performed. MS Baby Body, VIASYS, USA was used. Standard protocols 1 and proper reference values 2 were used. FRCp equals 115.3±41.2% pred (PReferences: 1Hammer J, Eber E (eds). Pediatric Pulmonary Function Testing, 2005, Basel, Karger. 2Hulskamp G et al: Am J Respir Crit Care Med 2003;168:1003-9. Supported by the project “Follow-up of children with perinatal burden” of EEA and Norway grants and by the grant NT/11444-5.

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Geert D’Haens (2007) studied this question.

synapsesocial.com/papers/69a602b9272dc2d784053705https://doi.org/10.1136/gut.2006.103564
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