Safety of immune checkpoint inhibitors: A systematic review of disproportionality analysis studies

Key Points

• Immune checkpoint inhibitors are linked to notable adverse events, raising safety concerns.
• Adverse events related to immune checkpoint inhibitors were analyzed across multiple studies, showing various degrees of seriousness.
• Systematic review methodology utilized disproportionality analysis across diverse clinical settings to assess event data.
• Findings underscore the importance of continued monitoring for safety in diverse populations receiving treatment.