Oral Microbial Diversity is Associated with Biologic Treatment and Metabolic Health Status but not with Disease Activity in Patients with Inflammatory Bowel Disease.

Key Points

• Oral microbial diversity is influenced positively by biologic treatment in patients with inflammatory bowel disease, indicating potential health benefits.
• Higher fasting insulin levels correlate with more diverse but unhealthy oral microbiota, suggesting metabolic implications for IBD patients.
• Observational analysis reveals no association between oral microbial diversity and inflammatory bowel disease disease activity, indicating a need for further exploration.
• These findings highlight the role of oral microbiota as a potential marker of metabolic health rather than disease activity in inflammatory bowel disease.