Molecular Improvement of IL ‐23 Inhibition Revealed by Single‐Cell RNA Sequencing in Concurrent Psoriasis and Systemic Lupus Erythematosus
Key Points
Molecular improvement of IL-23 inhibition occurs in concurrent psoriasis and systemic lupus erythematosus, impacting treatment strategies.
Single-cell RNA sequencing shows distinct cellular responses relevant to IL-23 modulation in these conditions.
Analysis focuses on concurrently affected individuals, providing insights into overlapping pathology of psoriasis and lupus.
These findings may enable targeted therapies for managing these co-occurring autoimmune diseases.
Abstract
The data that support the findings of this study are openly available in GEO at https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE299258, reference number GSE299258.