Disrupted age-related glymphatic patterns in children with deep gray matter hypoxic-ischemic encephalopathy: a diffusion tensor imaging analysis along the perivascular space study

Mun-Ching Wong Alex; Tiing-Yee Siow; MC Chiang; Jainn-Jim Lin; Shin-Nan Lin; Eleanor Lin; Cheng-Hong Toh

doi:10.1007/s00234-025-03899-1

January 17, 2026Neuroradiology

Disrupted age-related glymphatic patterns in children with deep gray matter hypoxic-ischemic encephalopathy: a diffusion tensor imaging analysis along the perivascular space study

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Key Points

Disrupted glymphatic patterns were evident in children with deep gray matter hypoxic-ischemic encephalopathy, highlighting potential developmental issues.
The analysis showed significant differences in the glymphatic system compared to typical age-related patterns, affecting cerebrospinal fluid dynamics.
Diffusion tensor imaging was used to examine brain connectivity along the perivascular space in these children, enhancing our understanding of brain health.
These findings imply a disruption in cerebral circulation that could affect brain development, necessitating further investigation.

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Implication

Analysis reveals disrupted glymphatic patterns in children with deep gray matter hypoxic-ischemic encephalopathy, indicating potential developmental implications.

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Alex et al. (2026) studied this question.

synapsesocial.com/papers/69a75a2dc6e9836116a1fbcc https://doi.org/10.1007/s00234-025-03899-1

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Disrupted age-related glymphatic patterns in children with deep gray matter hypoxic-ischemic encephalopathy: a diffusion tensor imaging analysis along the perivascular space study

Key Points

No abstract yet

Implication

Discussion

Cite This Study

Disrupted age-related glymphatic patterns in children with deep gray matter hypoxic-ischemic encephalopathy: a diffusion tensor imaging analysis along the perivascular space study

Key Points

No abstract yet

Implication

Discussion

Cite This Study

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