Minimal important difference of quadriceps maximal voluntary contraction (QMVC) in COPD: a prospective cohort study

Key Points

• Changes in quadriceps maximal voluntary contraction should be interpreted using specific minimum important difference estimates.
• Sex-specific estimates are vital for proper assessment of quadriceps strength in individuals with COPD.
• This study employed a prospective cohort approach to gather data on quadriceps strength changes over time.
• Identifying these differences may enhance personalized treatment strategies for patients with COPD.