March 3, 2026JAMA Network Open1 citationsOpen Access

Geriatric Syndromes and Mortality Among Hospitalized Older Adults

TAThiago J. Avelino-SilvaUniversity of California, San Francisco MRMaria Fernanda B. RomaHospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo ADAdriana F. DutraHospital do Coração

Key Points

Increased geriatric syndromes correlate with heightened 90-day mortality among hospitalized older adults.
The study identified a median of 5 geriatric syndromes in hospitalized older adults, indicating significant vulnerability.
Cohort analysis across varying clinical settings highlighted the need for multidomain assessments in care.
Integrating assessments may help identify risks, improving overall health outcomes in this population.

Abstract

This cohort study found that hospitalized older adults had a median of 5 geriatric syndromes, which were independently and incrementally associated with 90-day mortality. Multidomain assessments should be integrated into standard hospital care to identify and address vulnerabilities that commonly affect older adults with acute illness.

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