⌘+K

Pulse Explore Communities Researchers Journals

Home Communities Explore

January 27, 2026PharmaNutrition

Mitochondrial-derived peptides (Humanin, MOTS-c, and SHLP2) protect pancreatic islet cells and delay the onset and progression of type 2 diabetes mellitus in mice

Tiyesh Paul Oly Banerjee Sangeeta Das Bithin Kumar Maji Srikanta Goswami Sandip Mukherjee

View at Publisher

Ask AI

Bookmark

Share

Key Points

Mitochondrial-derived peptides show protective effects on pancreatic islet cells, delaying type 2 diabetes onset.
The specific peptides, Humanin, MOTS-c, and SHLP2, were effective in a mouse model, preventing metabolic disturbances.
The study utilized a mouse model to examine how these peptides influence diabetes progression.
Findings support the potential of mitochondrial-derived peptides as therapeutic agents for type 2 diabetes management.

No abstract yet

We only have this paper's title and publication details.

Read it at the source→

Ask about this paper

Answers are grounded in this paper and cite their sources.

Ask your own question…

Implication

Empirical analysis demonstrates mitochondrial-derived peptides delay type 2 diabetes progression in mice, indicating potential treatments.

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Paul et al. (2026) studied this question.

synapsesocial.com/papers/69a75a68c6e9836116a202a7 https://doi.org/10.1016/j.phanu.2026.100480

View at Publisher

Ask AI

Bookmark

Share

Keep reading

Synapse has enriched 10 related papers. Consider them for comparative context:

1Evaluation of anti-inflammatory activity of EGCG-loaded nanostructured lipid carriers on CFA-induced rheumatoid arthritis in experimental animalsPharmaNutrition · 2026
2Microbial metabolites as emerging Biomodulators of host function and disease susceptibilityPharmaNutrition · 2026
3Bioactive warriors from Solanaceous plants – An inclusive review on anticancer potential and its molecular mechanismsPharmaNutrition · 2026
4Ora-pro-nobis (Pereskia sp.) as an unconventional edible plant: Nutritional potential, bioactive compounds, and evidence related to non-communicable chronic diseasesPharmaNutrition · 2026
5Methodological gaps in research on pre-exercise caffeine supplementation and exercise-induced muscle damage: A systematic reviewPharmaNutrition · 2026
6Breast cancer insights: Significance of Murraya koenigii and their potential in prevention and therapeutic interventionPharmaNutrition · 2026
7Neuroprotective effects of an ethanol extracts of an anti-diabetic herbal mixture on Alzheimer’s disease-related biomarkers in high-glucose-induced insulin resistancePharmaNutrition · 2026
8Nicotinamide improves physiological outcomes in an arginine vasopressin rat model of pre-eclampsiaPharmaNutrition · 2025
9Flavonoids and macrophage polarization: Key players in the immunomodulation of cardiometabolic syndrome and related therapiesPharmaNutrition · 2025
10Aloe vera and its byproducts as sources of valuable bioactive compounds: Extraction, biological activities, and applications in various food industriesPharmaNutrition · 2025

More from PharmaNutrition

More from Ramakrishna Mission Vivekananda Educational and Research Institute

More from National Institute of Biomedical Genomics

More from Serampore College