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Social buffering of stress in rats: a multisystem meta-analysis and translational framework for stress resilience | Synapse
March 3, 2026
Social buffering of stress in rats: a multisystem meta-analysis and translational framework for stress resilience
AS
Alexey Sarapultsev
MK
Maria Komelkova
EG
Evgenii Gusev
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Key Points
Stress resilience is influenced by social buffering, providing important insights into how social interactions can mitigate stress effects.
The analysis covers various neurobiological systems that play a role in stress resilience and social buffering mechanisms in animal models.
Using a multisystem framework, the study integrates findings from different biological levels to offer a comprehensive view of stress adaptation.
These insights may translate to other species, highlighting the importance of social environments in enhancing stress resilience.
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Sarapultsev et al. (Tue,) studied this question.
synapsesocial.com/papers/69a75a69c6e9836116a20322
https://doi.org/https://doi.org/10.1016/j.physbeh.2026.115242