Case report evaluates hybrid imaging effectiveness in detecting cardiac sarcoidosis, suggesting alternative diagnosis methods.
Sarcoidosis is a systemic granulomatous disease of unknown cause. Approximately one fourth of all patients with sarcoidosis have clinical manifestations of cardiac involvement. Granulomas may involve the pericardium, myocardium and endocardium of both the ventricles, as well as the atria. Cardiac involvement is associated with poor prognosis and is definitely confirmed with endomyocardial biopsy. Given the invasiveness and risks of the procedure, other alternative diagnostic methods are used. In diagnosis and clinical assessment of disease activity broad spectrum of analysis is used: clinical examination, laboratory analysis (ACE, chitotriosidase), multi-detector computer tomography (MDCT), hybrid imaging (positron emission tomography with computed tomography - PET/ CT; positron emission tomography with magnetic resonance-PET/MR). In this case report we evaluate usefulness of hybrid imaging (FDG PET/CT) in detection of cardiac sarcoidosis.
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Grozdić-Milojević et al. (2018) studied this question.
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