Efficacy of Topical Beta‐Blockers in Managing Epidermal Growth Factor Receptor Inhibitor‐Related Paronychia and Pyogenic Granuloma‐Like Lesion: A Systematic Review and Meta‐Analysis

Key Points

• Topical beta-blockers may provide a beneficial management option for paronychia related to EGFR inhibitors, improving patient outcomes.
• In the review, findings indicate that topical beta-blockers are well-tolerated and effective in easing symptoms over the study period.
• The systematic review involves an analysis of existing data from randomized controlled trials focused on topical treatments for paronychia.
• These findings highlight the need for larger trials to validate treatment protocols and assess the long-term effectiveness of topical beta-blockers.