Vagus Nerve Stimulation in the Management of Neurodegenerative Diseases: A Systematic Review of Advances in Animal Research and Clinical Applications

Key Points

• Vagus nerve stimulation shows promise for managing neurodegenerative diseases by providing neuroprotection.
• In animal models, it achieves effects related to neuroprotection and anti-neuroinflammation in conditions like Alzheimer's.
• Systematic review highlights the need for further research into protective mechanisms of vagus nerve stimulation.
• Findings indicate potential clinical applications, yet further exploration is essential for validation.