An improved algorithm for genetic diagnostics of aggressive B-cell lymphomas in pediatric oncohematology: the experience of the Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology

Key Points

• Increased accuracy in identifying genetic subtypes of aggressive B-cell lymphomas allows for personalized treatment plans,
• The combined use of FISH and NGS methods in diagnostics improves molecular characterization, leading to better patient outcomes.
• Assessment of genetic features in pediatric oncohematology reveals significant implications for prognosis and treatment strategies.
• This approach highlights the potential for enhanced prognosis through tailored interventions, focusing on genetic aspects.