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March 3, 2026Journal of Clinical Medicine0 citationsOpen Access

Urgent and Emergent Endovascular Treatment of the Downstream Aorta Soon After Open Surgical Repair in Acute Type A Aortic Dissection: Analyzing Indications and Outcomes of an Institutional Case Series

PDPeter DonndorfTATheresa AnglesCSClemens Schafmayer

Key Points

  • Urgent or emergent thoracic endovascular aortic repair (TEVAR) demonstrates a substantial mortality risk, especially in cases of rupture.
  • Technical success rate for TEVAR was 100%, with zero postoperative mortality in true lumen collapse cases during the follow-up period.
  • Retrospective observational analysis across seven patients who had open surgical repair of type A aortic dissection from January 2024 to April 2025.
  • Findings underscore the necessity of timely TEVAR application to mitigate severe complications post-surgery, particularly in ruptured cases.

Abstract

Objectives: Thoracic endovascular aortic repair (TEVAR) is rarely indicated on an urgent or emergent basis soon after open surgical repair of type A aortic dissection (TAAD), and systematic data on clinical outcomes are therefore missing. In the present study, we analyze a contemporary case series regarding the outcome after urgent and emergent endovascular treatment of the downstream thoracic aorta, following open surgery for TAAD. Methods: The study was conducted as a retrospective observational analysis. From January 2024 until April 2025, seven patients (four male, aged 56.8 ± 5.6 years) were treated with TEVAR on an urgent or emergent basis within 48 h after open surgical repair of TAAD at our institution. In all seven patients, the initial dissection extended from the ascending to the abdominal aorta. All seven patients had previously received emergent open surgical repair by ascending aortic repair combined with hemiarch replacement (five patients) or total arch replacement, utilizing the frozen elephant trunk (FET) technique (two patients). Results: In four patients, the indication for urgent TEVAR was due to true lumen collapse (TLC) of the downstream aorta with resulting visceral or peripheral malperfusion symptoms. Three patients were treated on an emergent basis, due to rupture of the descending thoracic aorta with a resulting hemorrhage. Technical success of the TEVAR procedure was 100%. Thirty-day mortality was 0% in the TLC cases but 66% in the ruptured cases, where two of three patients died postoperatively due to the consequences of severe hemorrhagic shock. Within the surviving patients, no subsequent aortic events occurred during follow-up. Late mortality was 0%. The follow-up period was 15.7 ± 2.0 months. Conclusions: In our case series, mortality of urgent or emergent TEVAR soon after open surgical repair for TAAD is substantial, especially in patients that were treated due to acute rupture of the descending thoracic aorta and consecutive hemorrhagic shock. On the other hand, true lumen collapse with resulting malperfusion was successfully treated by instant TEVAR application in all patients without late aortic complications by the midterm follow-up.

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Donndorf et al. (2026) studied this question.

synapsesocial.com/papers/69a75abac6e9836116a20ecchttps://doi.org/10.3390/jcm15030936
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Early vs. Late Endovascular Extension Following Frozen Elephant Trunk Procedure: Effects on Clinical Outcomes and Aortic Remodeling2025 · 1 citations
  2. 2Complementary Thoracic Endovascular Aortic Repair (TEVAR) after Frozen Elephant Trunk for Residual Type A Aortic Dissection: Perioperative and Mid-Term Outcomes2024 · 5 citations
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