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March 3, 2026Neurogastroenterology & Motility2 citationsOpen Access

Revisiting the Incidence of Tardive Dyskinesia With Oral Metoclopramide Use: A Real‐World Epidemiology Study (2011–2020)

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RMRichard W. McCallumHPHenry P. ParkmanLNLinda A. Nguyen

Key Points

  • Uncommon incidence of tardive dyskinesia is observed with metoclopramide use, indicating it may be a safer option.
  • Evidence shows TD incidence is lower than previously estimated in instances of gastroparesis treatment.
  • Analysis using real-world data from 2011 to 2020 provides a contemporary perspective on TD risk with metoclopramide.
  • Highlights the need to reassess the risk-benefit profile of metoclopramide in managing gastroparesis patients.

Abstract

TD incidence is uncommon with metoclopramide use and lower than previously estimated in gastroparesis patients. These findings suggest metoclopramide may be a viable treatment option and warrant a reassessment of its risk-benefit profile in gastroparesis management.

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Cite This Study

McCallum et al. (2026) studied this question.

synapsesocial.com/papers/69a75abdc6e9836116a20f06https://doi.org/10.1111/nmo.70206
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