Effects of psilocybin on personality, psychiatric symptoms, and values: Exploring mediating effects of the acute psychedelic experience

Key Points

• Self-reported changes in values correlate with specific aspects of the acute psychedelic experience.
• Oceanic boundlessness and auditory alterations significantly mediate these value changes, indicating a strong connection.
• Exploratory analysis using self-report surveys in a healthy volunteer sample seeks to clarify how psilocybin affects personality.
• Findings are tentative, emphasizing the need for larger-scale studies to validate these results.

Abstract