This review explores how gut microbiota influences BDNF levels, suggesting new avenues for treating aging-related disorders.
Gut microbiota plays a critical role in regulating brain-derived neurotrophic factor (BDNF), thereby contributing to healthy aging and the improvement of neurodegenerative and neuropsychiatric disorders. This review explores the interactions among gut microbiota, BDNF, and aging within the Gut-Brain Axis framework. Evidence from animal and clinical studies indicates that probiotic supplementation and restoration of microbial balance enhance BDNF expression, improve cognitive function, and alleviate symptoms of depression, anxiety, Alzheimer
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Hwang et al. (2025) studied this question.
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