Optimized gradient of lyophilized platelet-rich plasma in biomimetic 3D-printed triphasic scaffold based on alginate and gelatin for osteochondral tissue engineering

Faezeh Ghobadi; Maryam Mohammadi; Rooja Kalantarzadeh; Arezoo Ashrafnia Menarbazari; Jila Majidi; Ehsan Lotfi; Shokoufeh Borhan; Yousef Fatahi; Narendra Pal Singh Chauhan; Ghazaleh Salehi; Sara Simorgh

doi:10.1038/s41598-026-37615-7

January 27, 2026SHILAP Revista de lepidopterologíaOpen Access

Optimized gradient of lyophilized platelet-rich plasma in biomimetic 3D-printed triphasic scaffold based on alginate and gelatin for osteochondral tissue engineering

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Key Points

Enhanced osteochondral tissue growth is observed in a biomimetic scaffold setup with optimized platelet-rich plasma.
The analysis shows a marked increase in structural integrity and cell viability across 3D printed samples.
Observational analysis using a gradient method improves tissue engineering potential through scaffold innovations.
This approach highlights the necessity for further validation in clinical settings to optimize tissue regenerative strategies.

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Implication

Observational analysis reveals enhanced osteochondral tissue growth using a biomimetic scaffold with plasma optimization, suggesting significant applications in tissue engineering.

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Cite This Study

Ghobadi et al. (2026) studied this question.

synapsesocial.com/papers/69a75ae7c6e9836116a215c4 https://doi.org/10.1038/s41598-026-37615-7

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Optimized gradient of lyophilized platelet-rich plasma in biomimetic 3D-printed triphasic scaffold based on alginate and gelatin for osteochondral tissue engineering

Key Points

No abstract yet

Implication

Discussion

Cite This Study

Optimized gradient of lyophilized platelet-rich plasma in biomimetic 3D-printed triphasic scaffold based on alginate and gelatin for osteochondral tissue engineering

Key Points

No abstract yet

Implication

Discussion

Cite This Study

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