Single-cell transcriptomics of Pacific white shrimp (Litopenaeus vannamei) hepatopancreas reveal immune and metabolic responses to AHPND-causing Vibrio parahaemolyticus

Key Points

• Cells in the hepatopancreas showed significant humoral immune responses to Vibrio parahaemolyticus, indicating immune adaptations.
• The transcriptomic analysis identified key immune and metabolic pathways activated during the response to the pathogen.
• Investigations included characterizing various cell types in the hepatopancreas for a comprehensive understanding.
• These findings provide insights that may lead to novel treatments or preventative measures against AHPND.