Lattice-oxygen-enhanced enzymatic activity: Eu-His:CeO2-X acting as a hydrolytic clusterzyme and fluorescence-sensor-array for the detection of biological phosphate esters (BPEs)

Key Points

• Hydrolytic activity was significantly enhanced by lattice oxygen, improving detection efficiency for biological phosphate esters.
• The fluorescence sensor array employing Eu-His:CeO2-X showed remarkable sensitivity, detecting low concentrations of phosphate esters.
• Assessment using a hydrolytic clusterzyme approach revealed that enzyme activity is linked to the presence of lattice oxygen in the structure.
• This work may enable advanced detection methods for biological phosphate esters, suggesting applications in biochemical analysis.