The predictive potential of surrogate indicators of insulin resistance for type 2 diabetic kidney disease

Key Points

Diabetic kidney disease risk increases with higher levels of insulin resistance indicators such as TyG and TyG-BMI.
TyG, TyG-BMI, and TG/HDL-C exhibit strong positive correlations with kidney disease risk in diabetes.

Structured PICO

Do surrogate indicators of insulin resistance (TyG, TyG-BMI, and TG/HDL-C) predict the risk of diabetic kidney disease in patients with type 2 diabetes mellitus?

Population

Patients with type 2 diabetes mellitus (T2DM)

Intervention

Surrogate indicators of insulin resistance (TyG, TyG-BMI, and TG/HDL-C)

Outcome

Diabetic kidney disease (DKD) risksurrogate

TyG, TyG-BMI, and TG/HDL-C are accessible and cost-effective indicators that can predict the risk of diabetic kidney disease in patients with type 2 diabetes.

Abstract

TyG, TyG-BMI, and TG/HDL-C are positively correlated with DKD risk in T2DM patients and demonstrate substantial predictive value, supporting their potential as accessible, cost-effective indicators for DKD risk assessment.

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