Rat models for arterial calcification associated with chronic kidney disease: a systematic review and meta-analysis

Key Points

• Arterial calcification is critically linked to chronic kidney disease in rat models, indicating an important pathological relationship.
• The meta-analysis reveals that various interventions directly influence the extent of arterial calcification observed in these models.
• This systematic review collates data from multiple sources, providing valuable insights into the mechanisms underlying arterial calcification in chronic kidney disease.
• Understanding these rat models can guide future studies on potential therapeutic interventions, highlighting a crucial area for ongoing research.