CD163 at the crossroads: a viral-exploited immunomodulator

Key Points

• CD163 plays a significant role in modulating immune response during viral infections, enhancing macrophage activity and cytokine release.
• Findings indicate that viral exploitation of CD163 can alter immune pathways, potentially impacting disease outcomes.
• Assessment focused on the interactions between CD163 and various viral pathogens, exploring their effect on cytokine signaling.
• This highlights the need for further investigation into CD163's role in immune modulation, addressing therapeutic implications for viral diseases.