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March 3, 2026Frontiers in Aging Neuroscience1 citationsOpen Access

Gamma-aminobutyric acid associated research in Parkinson’s disease: an exploratory trends analysis

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SZSheng-Qiang ZhouHunan Academy of Traditional Chinese MedicineFLFang LiuHunan Academy of Traditional Chinese MedicineYCYan-Jun ChenHunan University

Key Points

  • GABA is central to understanding mechanisms in Parkinson's disease, highlighting its importance.
  • The analysis reveals collaboration trends among authors from different institutions and countries.
  • GABA's interaction with α-synuclein and oxidative stress is crucial for ongoing research.
  • Future studies should explore GABA's link to non-motor symptoms like anxiety for comprehensive treatment.

Abstract

This study delineates a comprehensive knowledge structure of GABA and PD research. Enhanced collaboration among authors across institutions and countries is pivotal to advancing the field. The mechanism of GABA in the basal ganglia region is a focus of current research. The detrimental effects of α-synuclein and oxidative stress on the GABAergic system and the non-motor symptom of anxiety are likely to be the frontiers of future research.

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Cite This Study

Zhou et al. (2026) studied this question.

synapsesocial.com/papers/69a75b76c6e9836116a22cb3https://doi.org/10.3389/fnagi.2025.1655660
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