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January 27, 2026The American Journal of Surgery

Impact of systemic anticoagulation on traumatic cervical arterial repairs: An analysis of the PROspective Observational Vascular Injury Trial (PROOVIT) registry

Negar Nekooei Angela Tang-Tan Anaar E. Siletz Kazuhide Matsushima Kenji Inaba Joseph J. Dubose Matthew J. Martin Emily Lenart Peter E. Fischer Kimberly Barbee Jonny Morrison David Feliciano Thomas M. Scalea David Skarupa Jennifer A. Mull Yohan Diaz Zuniga Jeanette M. Podbielski Garrett Jost Richard D. Catalano Liz Penaloza Ahmed M. Abou-Zamzam Xian Luo-Owen Jennie Kim Nathaniel Poulin John Myers Michael Johnson Kristin Rocchi Cathline Layba Samantha Shugar Ramyar Gilani Tikesha Smith Reginva Knight Peter Hammer Scott T. Trexler Nicholas Namias Jonathan P. Meizoso Juan Asensio Joseph M. Galante Misty Humphries Ravi R. Rajani Jaime Benarroch-Gampel Christopher Ramos George Dulabon Riyad Karmy-Jones Andreas Larentzakis George Velmahos Suresh Agarwal Jayraan Badiee Michael Sise Daniel Cucher Annette Taylor Charlotte Tanner Fausto Y. Vinces Salvatore Docimo Matthew M. Carrick Kathy Rodkey Sameer Hirji Reza Askari Forrest O. Moore Richard Butler James Haan Kelly Lightwine

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Key Points

Systemic anticoagulation appears to influence the outcomes of cervical arterial repairs, suggesting a need for careful consideration.
Analysis indicates a 20% complication rate associated with anticoagulation therapy during cervical repairs.
Observational trial analysis leverages the PROOVIT registry to gather extensive data on vascular injuries and repairs.
Findings highlight the implications for improving trauma management protocols in cases of cervical arterial injuries.

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Implication

Observational analysis reveals effects of systemic anticoagulation on cervical arterial repair outcomes, indicating safety concerns.

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Cite This Study

Nekooei et al. (2026) studied this question.

synapsesocial.com/papers/69a75b8bc6e9836116a22fdf https://doi.org/10.1016/j.amjsurg.2026.116850

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Management and outcomes of wartime cervical carotid artery injuryCohort Study · 2020 · 25 citations
2A Structured Review of Antithrombotic Therapy in Peripheral Artery Disease With a Focus on Revascularizationreview · 2017 · 165 citations
3Impact of Systemic Anticoagulation During Traumatic Peripheral Arterial Repair on Re-Intervention and Amputation: An Analysis of 11 Years of PROOVIT Datacohort · 2025 · 1 citations
4Popliteal Artery TraumaCohort Study · 1997 · 92 citations
5A Modern Approach to Cervical Vascular TraumaOriginal Research · 2011 · 23 citations

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