The role of neoadjuvant therapy in elderly patients with T1b-T2N + esophageal cancer: a population-based cohort study

Key Points

• Neoadjuvant therapy provides a notable survival benefit over upfront surgery for elderly patients.
• Patients receiving neoadjuvant therapy showed improved outcomes in T1b-T2N+ esophageal cancer cases.
• This cohort analysis evaluated the effects of neoadjuvant therapy compared to surgery alone.
• Findings suggest that neoadjuvant therapy could be an effective intervention for older patients.