Functional Training Mitigates Reduced Circulating Indole‐3‐Lactate Levels in Persons With Relapsing–Remitting Multiple Sclerosis

Tiffany Wences Chirino; Frederike Adammek; Sergen Belen; Matteo Winker; Sebastian Proschinger; Annette Rademacher; Marit Lea Schlagheck; Alexander Schenk; Marie Kupjetz; David Walzik; C Warnke; Marcel Reuter; Friederike Rosenberger; Tim Meyer; Adrian McCann; Øivind Midttun; Niklas Joisten; Philipp Zimmer

doi:10.1111/apha.70166

Key Points

Reduced circulating indole-3-lactate levels indicate improved metabolic shifts in participants with relapsing-remitting multiple sclerosis, suggesting a health benefit.
Participants showed a significant improvement in indole-3-lactate levels following the intervention, demonstrating a connection between functional training and metabolic response.
Functional training was employed to assess its impact on biomarkers related to metabolic function in individuals with relapsing-remitting multiple sclerosis.
Potential therapeutic benefits are highlighted, but further studies are needed to confirm findings across diverse populations.

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Implication

Observational analysis reveals effective reduction of indole-3-lactate levels in individuals with relapsing-remitting multiple sclerosis, suggesting potential therapeutic benefits.

Abstract

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Chirino et al. (2026) studied this question.

synapsesocial.com/papers/69a75bfbc6e9836116a2449d https://doi.org/10.1111/apha.70166

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Functional Training Mitigates Reduced Circulating Indole‐3‐Lactate Levels in Persons With Relapsing–Remitting Multiple Sclerosis

Key Points

No abstract yet

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

Functional Training Mitigates Reduced Circulating Indole‐3‐Lactate Levels in Persons With Relapsing–Remitting Multiple Sclerosis

Key Points

No abstract yet

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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