Observational analysis reveals the crucial role of NF-κB signaling in uveal melanoma malignancy, highlighting the need for genetic manipulation tactics.
NF-κB signaling, particularly the canonical branch, is required for UM malignancy, while noncanonical signaling is linked with high-risk features. Branch-specific genetic manipulations and clinically relevant models should be employed in future research to maximize therapeutic strategies.
No takes yet. Share an insight, caveat, or question.
Jalali et al. (2025) studied this question.
Synapse has enriched 5 related papers. Consider them for comparative context: