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March 3, 2026International Immunopharmacology1 citations

Molecular and functional characterization of a novel Toll-like receptor 9-specific DNA aptamer with therapeutic potential

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MFMariya FarooqBABilal AhmadAKAnwar Khan

Key Points

  • The DNA aptamer demonstrates binding specificity to toll-like receptor 9, indicating strong potential for therapeutic application.
  • Binding affinity measured is notably high, with a KD (dissociation constant) value less than 10nM, showcasing effectiveness.
  • Molecular and functional characterization methods employed elucidate the aptamer's mechanisms of action and therapeutic capabilities.
  • Findings suggest promising applications in immune modulation, highlighting the need for further development in therapeutic contexts.
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Cite This Study

Farooq et al. (2026) studied this question.

synapsesocial.com/papers/69a75c2fc6e9836116a24c26https://doi.org/10.1016/j.intimp.2025.116134
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