Why the study?
Purulent pericarditis is rare in the modern era but remains a rapidly progressive and highly fatal infection requiring early diagnosis and appropriate therapy.
18F-FDG PET/CT can be a valuable diagnostic tool for identifying difficult-to-diagnose purulent pericarditis, enabling prompt surgical and medical intervention.
May enable prompt intervention in purulent pericarditis; extends 18F-FDG PET/CT utility and remains hypothesis-generating.
Although purulent pericarditis is rare in the modern era, early diagnosis and appropriate therapy with antibiotics and drainage are critical because it remains a rapidly progressive and highly fatal infection. Purulent pericarditis typically occurs as a secondary infection through hematogenous dissemination or contiguous spread from an intrathoracic infection, with most cases occurring in immunocompromised individuals. Herein, we report the case of a 52-year-old male patient with a history of diabetes mellitus who had difficult-to-diagnose chest pain. He was ultimately diagnosed with purulent pericarditis using ¹⁸F-fluorodeoxyglucose positron emission tomography/computed tomography, then treated via surgical drainage, pericardiectomy, and long-term antibiotic therapy.
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Isa et al. (2026) studied this question.
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