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March 3, 2026Frontiers in Aging Neuroscience6 citationsOpen Access

Trends and cross-country inequalities in the global burden of Alzheimer’s disease and other dementias among adults aged 65+ years, 1990–2021: a population based study with projections into 2050

SLSibo LiuGWGuozhi WuXMXiao Ma

Key Points

  • The global burden of dementia has nearly tripled from 1990 to 2021, indicating a serious concern.
  • Population ageing and growth significantly contribute to the increased prevalence of dementia globally.
  • Observational analysis of global data reveals key trends and disparities in dementia cases by region and gender.
  • Strategies for prevention and early diagnosis are essential to manage dementia effectively, given these growing challenges.

Abstract

The global number of people living with dementia nearly tripled from 1990 to 2021, mainly due to increases in population ageing and growth. The findings emphasize the need for comprehensive strategies to address ADOD, including prevention, early diagnosis, and effective management, with a focus on gender and regional disparities.

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Cite This Study

Liu et al. (2026) studied this question.

synapsesocial.com/papers/69a75c8ac6e9836116a257echttps://doi.org/10.3389/fnagi.2025.1683158
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