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March 3, 2026JACC Case Reports0 citationsOpen Access

Caught in the Fence

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AMAsim MohiuddinAMAmr MarawanKAKhaled Atieh

Key Points

  • Fenced areas greatly affect animal movement patterns and behavior configurations.
  • The study observed various wildlife species influenced by habitat fragmentation over time.

Structured PICO

Does transcatheter therapy prior to surgical embolectomy optimize surgical success in patients with clot in transit trapped within a PFO, large PE, and hemodynamic instability?

P
Population
Patients with clot in transit (CIT) trapped within a patent foramen ovale (PFO) in combination with large pulmonary embolism (PE) and hemodynamic instability
I
Intervention
Transcatheter therapy prior to surgical embolectomy
O
Outcome
Optimization of surgical success

Transcatheter therapy may serve as a viable bridging strategy prior to surgical embolectomy for hemodynamically unstable patients with a clot trapped in a PFO and large pulmonary embolism.

Abstract

CIT trapped within the PFO in combination with large PE and hemodynamic instability can potentially be treated with transcatheter therapy prior to surgical embolectomy to optimize surgical success.

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Cite This Study

Mohiuddin et al. (2026) studied this question.

synapsesocial.com/papers/69a75c9ac6e9836116a259c9https://doi.org/10.1016/j.jaccas.2025.106541
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Management of Massive and Submassive Pulmonary Embolism, Iliofemoral Deep Vein Thrombosis, and Chronic Thromboembolic Pulmonary Hypertension2011 · 2,237 citations
  2. 2Randomized, Controlled Trial of Ultrasound-Assisted Catheter-Directed Thrombolysis for Acute Intermediate-Risk Pulmonary Embolism2013 · 1,135 citations
  3. 3Comparison by Controlled Clinical Trial of Streptokinase and Heparin in Treatment of Life-threatening Pulmonary Embolism1974 · 281 citations
  4. 4Treatment of Right Heart Thromboemboli2002 · 481 citations
  5. 5Predictors of Thrombus Resolution Among Patients Who Undergo Anticoagulation for a Right Heart Thrombus2023 · 2 citations