Recombinant bovine lactoferrin ameliorates cold stress-induced immunosuppression by modulating the gut microbiota in mice

Key Points

• Recombinant bovine lactoferrin enhances immune response under cold stress conditions by positively modulating gut microbiota.
• The study demonstrated significant improvement in immunosuppression among mice exposed to cold stress, with noticeable changes in gut microbiota diversity.
• Gut microbiota modulation was assessed using microbial analysis techniques to establish the link between lactoferrin and immune function.
• Findings suggest the potential for using recombinant bovine lactoferrin as a therapeutic approach for stress-related immune dysfunction in animals.