Oxidative Hetero Coupling Reaction of 2-Oxindoles with Phenols Using Guanidinium Hypoiodite Catalyst

Key Points

• 3-aryl-2-oxindole scaffolds were constructed efficiently under mild conditions using a novel catalyst.
• The method resulted in moderate enantioselectivity for enantio-enriched products with a chiral organocatalyst.
• The catalytic system employed guanidinium and hypoiodite to induce the reaction between 2-oxindoles and phenols effectively.
• This reaction highlights the potential for developing new synthetic pathways in organic chemistry.